5-MeO-DMT Freebase

 18,00 300,00

Product Name: 5-MeO-DMT Freebase
Other Name(s): The God Molecule, Toad, 5-methoxy-N,N-dimethyltryptamine
IUPAC Name: 3-[2-(dimethylamino)ethyl]-5-methoxyindole

CAS: 1019-45-0
Purity (GCMS): 97,98 %
Molar Mass: 218.3 g/mol


SKU: N/A Category:


5 MeO-DMT Freebase:

DISCLAIMER: The following text is for educational purposes only, our products are strictly for research purposes and not for human consumption!

The origin of 5-MeO-DMT:

5-MeO-DMT, or 5-methoxy-N,N-dimethyltryptamine, is a naturally occurring compound found in various plant and animal species. It is chemically related to DMT (dimethyltryptamine) and shares some similarities in terms of its effects, although it tends to produce more intense and short-lived experiences.

Here are the primary natural sources of 5-MeO-DMT:

  1. Bufo Alvarius Toad Venom: One of the most well-known sources of 5-MeO-DMT is the secretions from the Colorado River toad, scientifically known as Bufo alvarius. These toads secrete a venom that contains 5-MeO-DMT, among other compounds. Indigenous peoples in some regions have used these secretions in traditional rituals for centuries. The substance can be extracted from the toad venom for recreational or ceremonial use, although this practice is controversial and may have ethical and ecological concerns.
  2. Various Plant Species: 5-MeO-DMT can also be found in some plant species, although its presence in plants is less common compared to its presence in certain toad species. Some plants that contain 5-MeO-DMT include species of the Anadenanthera and Virola genera. Indigenous groups in South America have used these plants in their traditional shamanic practices.
  3. Chemical Synthesis: In addition to natural sources, 5-MeO-DMT can be synthesized in a laboratory setting.

How 5-MeO-DMT works in the brain:

5-MeO-DMT, also known as 5-methoxy-N,N-dimethyltryptamine, is a powerful and potent psychedelic compound. It produces intense, short-lasting, and profound altered states of consciousness when ingested or inhaled. While the exact mechanisms of how 5-MeO-DMT works in the brain are not fully understood, its effects are thought to be primarily mediated through its interaction with the serotonin system and its agonism at serotonin receptors.

Here’s a simplified explanation of how 5-MeO-DMT works in the brain:

  1. Serotonin Receptor Agonism: 5-MeO-DMT is structurally similar to serotonin, a neurotransmitter responsible for regulating mood, emotions, and various physiological functions. It acts as an agonist, meaning it binds to and activates specific serotonin receptors in the brain.
  2. Altered Perception and Consciousness: By binding to serotonin receptors, particularly the 5-HT2A receptor, 5-MeO-DMT alters the normal patterns of serotonin signaling. This disruption in neurotransmission is believed to be responsible for the profound changes in perception, consciousness, and sensory experiences that users report during a 5-MeO-DMT trip.
  3. Rapid Onset and Intensity: One distinctive feature of 5-MeO-DMT is its rapid onset of action and intense effects. Within seconds of inhalation or ingestion, users often experience a dramatic shift in consciousness, described as a complete dissolution of the self and a merging with the universe.
  4. Short Duration: The effects of 5-MeO-DMT are typically very short-lived, usually lasting only a few minutes to around half an hour. Despite the brief duration, the experiences can be extremely profound and transformative.
  5. Neuroplasticity and Long-Term Effects: Some research suggests that psychedelic compounds like 5-MeO-DMT may promote neuroplasticity, which is the brain’s ability to reorganize and form new neural connections. This potential for neuroplasticity could underlie some of the reported long-term psychological and therapeutic benefits of psychedelic experiences, but more research is needed in this area.

Traditional and modern use of 5-MeO-DMT:

5-MeO-DMT is used by a variety of individuals for different purposes. Its usage spans several groups, including:

  1. Indigenous and Shamanic Traditions: In some indigenous cultures, particularly in South America, certain plant sources of 5-MeO-DMT have been used for centuries as part of shamanic and healing rituals. Indigenous shamans or healers might administer these substances to facilitate spiritual experiences, healing, and insights.
  2. Psychonauts and Spiritual Seekers: Some individuals in Western cultures are drawn to 5-MeO-DMT for its potential to induce powerful mystical or spiritual experiences. They may use it as a tool for self-exploration, personal growth, and to seek insights into the nature of consciousness and existence.
  3. Psychedelic Therapists: In recent years, there has been growing interest in the therapeutic potential of psychedelics, including 5-MeO-DMT. Some therapists, often working in clinical or research settings, are exploring the use of 5-MeO-DMT in combination with psychotherapy to treat various mental health conditions or to facilitate personal transformation.
  4. Recreational Users: Unfortunately, some individuals use 5-MeO-DMT for recreational purposes, seeking intense and mind-altering experiences. It’s important to note that this can be risky, as the powerful effects of 5-MeO-DMT can be overwhelming and are not always predictable.
  5. Self-Exploration and Personal Development: Some people use 5-MeO-DMT as a means of self-exploration, personal development, or as a catalyst for creativity and insight. They may engage in these experiences in a responsible and intentional manner.

It’s essential to emphasize that the use of 5-MeO-DMT can be associated with both potential benefits and risks. The intensity of the experience and the potential for profound psychological and spiritual effects make it important for users to approach it with caution, respect, and in a safe setting.

It’s important to note that 5-MeO-DMT is a potent substance with the potential for both positive and negative psychological effects. Its use should be approached with caution and in a safe and controlled environment, ideally under the supervision of experienced individuals.

Please keep in mind that the legal status of 5-MeO-DMT varies from country to country, and it may be considered a controlled substance in many places. We do not endorse or encourage the use of illegal substances. This information is provided solely for educational purposes.


Additional information


0.25 gram, 0.5 gram, 1 gram, 10 gram, 2 gram, 5 gram